The film tells the story of a female astronaut who, upon returning to Earth from a life-changing mission in space, begins to slowly unravel and lose touch with reality. Her psychological decline culminates in a fevered cross-country trip with violent intentions in this complex, thrilling and darkly comedic character study.

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Cast: Natalie Portman, Jon Hamm, Dan Stevens, Zazie Beetz, Nick Offerman, Ellen Burstyn, Tig Notaro, Colman Domingo